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Ausgewählte Publikationen der Professur Ernährungsphysiologie

Dresen E, Weißbrich C, Fimmers R, Putensen C, Stehle P. Medical high-protein nutrition therapy and loss of muscle mass in adult ICU patients: A randomized controlled trial. Clinical Nutrition. 2021; 40 (4): 1562-1570. doi: 10.1016/j.clnu.2021.02.021.

Leischner C, Egert S, Burkard M, Venturelli S: Potential Protective Protein Components of Cow’s Milk against Certain Tumor Entities. Nutrients 2021; 13, 1974. https://doi.org/10.3390/nu13061974

Frank J, Kisters K, Stirban OA, Obeid R, Lorkowski S, Wallert M, Egert S, Podszun MC, Eckert GP, Pettersen JA, Venturelli S, Classen HG, Golombek J. The role of biofactors in the prevention and treatment of age-related diseases. Biofactors 2021 Mar 26. doi: 10.1002/biof.1728

Melo van Lent D, Egert S, Wolfsgruber S, Kleineidam L, Weinhold L, Wagner-Thelen H, Maier W, Jessen F, Ramirez A, Schmid M, Scherer M, Riedel-Heller SG, Wagner M. Eicosapentaenoic Acid Is Associated with Decreased Incidence of Alzheimer's Dementia in the Oldest Old. Nutrients 2021; Jan 30;13(2):461. doi: 10.3390/nu13020461

Lambidou M, Alteheld B, Fimmers R, Jochum F, Nomayo A, Stehle P. Impact of an Infant Formula Containing a Novel Fat Blend (Cow's Milk Fat, Fish and Vegetable Oil) and Prebiotics on Stool Fatty Acid Soaps and Erythrocyte Fatty Acid Profiles in Full-Term Healthy Newborns. Annals of Nutrition and Metabolism. 2021 Apr 30:1-8. doi: 10.1159/000515705. Online ahead of print.

Barbaresko J, Lellmann AW, Schmidt A, Lehmann A, Amini AM, Egert S, Schlesinger S, Nöthlings U. Dietary Factors and Neurodegenerative Disorders: An Umbrella Review of Meta-Analyses of Prospective Studies. Advances in Nutrition 2020;11(5):1161-1173. doi: 10.1093/advances/nmaa053

Maretzke F, Bechthold A, Egert S, Ernst JB, Melo van Lent D, Pilz S, Reichrath J, Stangl GI, Stehle P, Volkert D, Wagner M, Waizenegger J, Zittermann A, Linseisen J. Role of Vitamin D in Preventing and Treating Selected Extraskeletal Diseases - An Umbrella Review. Nutrients 2020 Mar 31;12(4):969. doi: 10.3390/nu12040969

Schönknecht YB, Crommen S, Stoffel-Wagner B, Coenen M, Fimmers R, Holst JJ, Simon MC, Stehle P, Egert S. Acute Effects of Three Different Meal Patterns on Postprandial Metabolism in Older Individuals With a Risk Phenotype for Cardiometabolic Diseases: A Randomized Controlled Crossover Trial. Molecular Nutrition and Food Research 2020 May;64(9):e1901035. doi: 10.1002/mnfr.201901035

Webb LA, Sadri H, Schuh K, Egert S, Stehle P, Meyer I, Koch C, Dusel G, Sauerwein H: Branched-chain amino acids: Abundance of their transporters and metabolizing enzymes in adipose tissue, skeletal muscle and liver of dairy cows at high or normal body condition. Journal of Diary Science 2020 Mar;103(3):2847-2863. doi: 10.3168/jds.2019-17147

Siener R, Machaka I, Alteheld B, Bitterlich N, Metzner C: Effect of Fat-Soluble Vitamins A, D, E and K on Vitamin Status and Metabolic Profile in Patients with Fat Malabsorption with and without Urolithiasis. Nutrients 2020 Oct 12;12(10):3110. doi: 10.3390/nu12103110.

Diekmann C, Wagner M, Huber H, Preuß M, Preuß P, Predel HG, Stoffel-Wagner B, Fimmers R, Stehle P, Egert S: Acute Impact of Dietary Pattern and Walking on Postprandial Attention, Mood, and Satiety in Older Adults: A Randomized Crossover Trial. Nutrients. 2019 Sep 26;11(10). pii: E2294. doi: 10.3390/nu11102294.

Diekmann C, Huber H, Preuß M, Preuß P, Predel HG, Stoffel-Wagner B, Fimmers R, Stehle P, Egert S: Moderate postmeal walking has no beneficial effects over resting on postprandial lipemia, glycemia, insulinemia, and selected oxidative and inflammatory parameters in older adults with a cardiovascular disease risk phenotype: A randomized crossover trial. Journal of Nutrition 2019 Jul 18. pii: nxz148. doi: 10.1093/jn/nxz148 [Epub ahead of print].

Dresen E, Weißbrich C, Bühlmeier J, Weisheit C, Egert S, Putensen C, Stehle P. Retrospektive Evaluation der Umsetzung einer klinikinternen Handlungsanweisung zur Ernährungstherapie von Intensivpatienten. Aktuelle Ernährungsmedizin. 2019; 44 (04): 237-247. doi: 10.1055/a-0915-4994.

Ströhle A, Richter M, Gonzáles-Gross M, Neuhäuser-Berthold M, Wagner KH, Leschik-Bonnet E, and Egert S for the German Nutrition Society (DGE): The 2018 revised D-A-CH-reference-values for the intake of vitamin B 12 for the prevention of deficiency and beyond. Molecular Nutrition and Food Research 2019 Mar;63(6):e1801178.

Webb LA, Sadri H, von Soosten D, Dänicke S, Egert S, Stehle P, Sauerwein H: Changes in tissue abundance and activity of enzymes related to branched-chain amino acid catabolism in dairy cows during early lactation. Journal of Diary Science 2019 Apr;102(4):3556-3568. doi: 10.3168/jds.2018-14463.

Burak C, Wolffram S, Zur B, Langguth P, Fimmers R, Alteheld B, Stehle P, Egert S: Effect of alpha-linolenic acid in combination with the flavonol quercetin on markers of cardiovascular disease risk in healthy, non-obese adults: a randomized double-blinded placebo-controlled crossover trial. Nutrition 2019 Feb;58:47-56.

Kent DS, Remer T, Blumenthal C, Hunt S, Simonds S, Egert S, Gaskin KJ: 13C-Mixed Triglyceride Breath test as an indirect pancreatic function test in cystic fibrosis neonates. Journal of Pediatric Gastroenterology & Nutrition 2018 May;66(5):811-815.

van der Lee SJ, Teunissen C, Pool R, Shipley MJ, Teumer A, Chouraki V, Melo-van-Lent D, Tynkkynen J, Fischer K, Hernesniemi J, Metspalu A, Singh-Manoux A, Verhoeven A, Willemsen G, de Leeuw F, Wagner H, van Dongen J, Hertel J, Budde K, van Dijk KW, Weinhold L, Ikram MA, Pietzner M, Perola M, Wagner M, Friedrich N, Slagboom PE, Scheltens P, Yang Q, Gertzen RE, Egert S, Hankemeier T, van Beijsterveld T, Ramachandran V, Maier W, Peeters C, Grabe HJ, Ramirez A, Seshadri S, Haller T, Kivimäki M, Salomaa V, Demirkan A, Boomsma D, van der Flier WM, Amin N, van Duijn CM: Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies. Alzheimer's and Dementia 2018 Jun;14(6):707-722.

Penczynski KJ, Herder C, Krupp D, Rienks J, Egert S, Bolzenius K, Wudy SA, Roden M, Remer T, Buyken AE: Flavonoid intake from fruit and vegetables during adolescence is prospectively associated with a favourable risk factor profile for type 2 diabetes in early adulthood. European Journal of Nutrition 2018, Feb 21 [Epub ahead of print].

Egert S, Stratmann B, Lee-Barkey YH, Stehle P, Tschoepe D, Wahrburg U: Effects of a hypoenergetic diet rich in plant alpha-linolenic acid on fatty acid composition of serum phospholipids in overweight and obese patients with metabolic syndrome. Nutrition 2018 May;49:74-80.

Armborst D, Metzner C, Alteheld B, Bitterlich N, Rösler D, Siener R: Impact of a Specific Amino Acid Composition with Micronutrients on Well-Being in Subjects with Chronic Psychological Stress and Exhaustion Conditions: A Pilot Study. Nutrients 2018 Apr 29;10(5):551. doi: 10.3390/nu10050551.

Kleist B, Wahrburg U, Stehle P, Schomaker R, Greiwing A, Stoffel-Wagner B, Egert S: Moderate walking enhances the effects of a hypo-energetic diet on fat mass loss and serum insulin in overweight and obese adults in a 12-week randomized controlled trial. Journal of Nutrition 2017; 147(10): 1875-1884.

Burak C, Wolffram S, Zur B, Langguth P, Fimmers R, Alteheld B, Stehle P, Egert S: Effect of alpha-linolenic acid supplementation in combination with quercetin and conversion to n-3 long-chain polyunsaturated fatty acids in humans: a randomized double-blinded placebo-controlled crossover trial. British Journal of Nutrition 2017 Mar;117(5):698-711.

Burak C, Brüll V, Langguth P, Zimmermann BZ, Stoffel-Wagner B, Sausen U, Stehle P, Wolffram S, Egert S: Higher plasma quercetin levels following oral administration of an onion skin extract compared with pure quercetin dihydrate in humans. European Journal of Nutrition 2017 Feb;56(1):343-353.

Brüll V, Burak C, Stoffel-Wagner B, Wolffram S, Nickenig G, Müller C, Langguth P, Alteheld B, Stehle P, Egert S: Acute intake of quercetin does not influence postprandial blood pressure and endothelial function in overweight-to-obese adults with hypertension in a randomized double-blinded placebo-controlled crossover trial. European Journal of Nutrition 2017; 56(3): 1347-1357.

Brüll V, Burak C, Stoffel-Wagner B, Wolffram S, Nickenig G, Müller C, Langguth P, Alteheld B, Stehle P, Egert S: No effects of quercetin on serum leptin and adiponectin concentrations in overweight-to-obese patients with hypertension: a randomized double-blinded placebo-controlled crossover trial. European Journal of Nutrition 2017; 56(7):2265-2275.

Jochum F, Alteheld B, Meinardus P, Dahlinger N, Nomayo A, Stehle P: Mothers' Consumption of Soy Drink But Not Black Tea Increases the Flavonoid Content of Term Breast Milk: A Pilot Randomized, Controlled Intervention Study. Annals of Nutrition and Metabolism. 2017;70(2):147-153. doi: 10.1159/000471857.

Petersen B, Egert S, Bosy-Westphal A, Müller MJ, Wolffram S, Hubbermann EM, Rimbach G, Schwarz K: Plasma flavonol and quercetin concentration after oral quercetin or quercetin glycosides supplementation comparing quercetin aglycone capsules to different apple sources. Food Research International 2016; 88: 159-165.

Wolf E, Utech M, Stehle P, Büsing M, Helfrich HP, Stoffel-Wagner B, Egert S, Alteheld B, Riege R, Knapp A, Ellinger S: Oral high-dose vitamin D dissolved in oil maintains physiological serum 25-hydroxy-vitamin D in obese patients after sleeve gastrectomy – a double-blind, randomized, and placebo-controlled trial. Obesity Surgery 2016 Aug;26(8):1821-9.

Brüll V, Burak C, Stoffel-Wagner B, Wolffram S, Nickenig G, Müller C, Langguth P, Alteheld B, Fimmers R, Naaf S, Zimmermann BF, Stehle P, Egert S: Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-)hypertension: a randomised double-blinded placebo-controlled crossover trial. British Journal of Nutrition 2015; 114(8):1263-77.

Heer M, Egert S: Nutrients other than carbohydrates: their effects on glucose homeostasis in humans. Diabetes Metabolism Research and Reviews 2015 Jan;31(1):14-35.

Chaborski K, Bitterlich N, Alteheld B, Parsi E, Metzner C: Placebo-controlled dietary intervention of stress-induced neurovegetative disorders with a specific amino acid composition: a pilot-study. Nutrition Journal 2015 May 6;14:43. doi: 10.1186/s12937-015-0030-3.

Krupp D, Shi L, Egert S, Wudy S, Remer T: Prospective relevance of fruit and vegetable consumption and salt intake during adolescence for blood pressure in young adulthood. European Journal of Nutrition 2014; 144(10): 1586-93.

Egert S, Baxheinrich A, Lee-Barkey YH, Tschoepe D, Wahrburg U, Stratmann B: Effects of an energy-restricted diet rich in plant alpha-linolenic acid on systemic inflammation and endothelial function in overweight-to-obese patients with metabolic syndrome traits. British Journal of Nutrition 2014; 112: 1315-1322.

Goletzke J, Buyken AE, Joslowski G, Bolzenius K, Remer T, Carstensen M, Egert S, Nöthlings U, Rathmann W, Roden M, Herder C: Increased intake of carbohydrates from sources with a higher glycemic index and lower consumption of whole grain during puberty are prospectively associated with higher IL-6 concentrations in younger adulthood among healthy individuals. Journal of Nutrition 2014; Oct;144(10):1586-93.

Egert S, Tereszczuk J, Wein S, Frank J, Rimbach G, Müller MJ, Wolffram S: Simultaneous ingestion of dietary proteins reduces the bioavailability of galloylated catechins from green tea in humans. European Journal of Nutrition 2013; 52(1): 281-288.

Egert S, Lindenmeier M, Harnack K, Krome K, Erbersdobler HF, Wahrburg U, Somoza V: Margarines fortified with -linolenic acid, eicosapentaenoic acid, or docosahexaenoic acid alter the fatty acid composition of erythrocytes but do not affect the antioxidant status of healthy adults. Journal of Nutrition 2012; 142(9): 1638-1644.

Egert S, Rimbach G, Huebbe P: APOE genotype - from geographic distribution to function and to responsiveness to dietary factors. Proceedings of the Nutrition Society 2012; 71(3): 410-424.

Spinneker A, Egert S, González Gross M, Breidenassel C, Albers U, Stoffel-Wagner B, Huybrechts I, Manios Y, Venneria E, Molnar D, Widhalm K, Moreno L, Stehle P, on behalf of the HELENA Study group: Lipid, lipoprotein and apolipoprotein profiles in healthy European adolescents and its associations with gender, biological maturity and body fat - The HELENA Study. European Journal of Clinical Nutrition 2012; 66(6): 727-735.

Egert S, Wolffram S, Schulze B, Langguth P, Hubbermann EM, Schwarz K, Adolphi B, Bosy-Westphal A, Rimbach G, Müller MJ: Enriched cereal bars are more effective in increasing plasma quercetin compared with quercetin from powder-filled hard capsules. British Journal of Nutrition 2012; 107(4): 539-546.

Rimbach G, Egert S, de Pascual-Teresa P: Chocolate - (un)healthy source of polyphenols? Genes and Nutrition 2011, 6(1): 1-3.

Graf S, Egert S, Heer M: Effects of whey protein supplements on metabolism - Evidence from human intervention studies. Current Opinion in Clinical Nutrition and Metabolic Care 2011, 14(6):569-80.

Huebbe P, Rimbach G, Siegert S, Moehring J, Boesch-Saadatmandi C, Most E, Pallauf J, Egert S, Müller MJ, Schreiber S, Nöthlings U, Nebel A: APOE ε4 is associated with higher vitamin D levels in targeted replacement mice and humans. FASEB Journal 2011, 25(9): 3262-70.

Egert S, Rimbach G, Müller MJ: No evidence for a thermic effect of the dietary flavonol quercetin – a pilot study in healthy normal weight women. European Journal of Applied Physiology 2011, 111(5): 869-73.

Egert S, Rimbach G: Which sources of flavonoids - complex diets or dietary supplements? Advances in Nutrition 2011, 2: 1-8.

Egert S, Stehle P: Impact of n-3 fatty acids on endothelial function - results from human interventions studies. Current Opinion in Clinical Nutrition and Metabolic Care 2011, 14(2): 121-31.

Egert S, Kratz M, Kannenberg F, Fobker M, Wahrburg U: Effects of low-fat and high-fat diets rich in monounsaturated fatty acids on serum lipids, LDL size and indices of lipid peroxidation in healthy non-obese men and women when consumed under controlled conditions. European Journal of Nutrition 2011, 50(1): 71-9.

Metzner CE, Folberth-Vögele A, Bitterlich N, Lemperle M, Schäfer S, Alteheld B, Stehle P, Siener R: Effect of a conventional energy-restricted modified diet with or without meal replacement on weight loss and cardiometabolic risk profile in overweight women. Nutrition and Metabolism (Lond). 2011 Sep 22;8(1):64. doi: 10.1186/1743-7075-8-64.

Boomgaarden I, Egert S, Müller MJ, Wolffram S, Rimbach G, Döring F: Quercetin supplementation and its effect on human monocyte gene expression profiles in vivo. British Journal of Nutrition 2010, 104(3): 336-45.

Boesch-Saadatmandi C, Egert S, Schrader C, Coumoul X, Barouki R, Müller MJ, Wolffram S, Rimbach G: Effect of quercetin on paraoxonase 1 activity - studies in cultured cells, mice and humans. Journal of Physiology and Pharmacology 2010, 61(1): 99-105.

Egert S, Boesch-Saadatmandi C, Wolffram S, Rimbach G, Müller MJ: Serum lipid and blood pressure responses to quercetin vary in overweight patients by apolipoprotein E genotype. Journal of Nutrition 2010, 140(2): 278-84.

Siener R, Alteheld B, Terjung B, Junghans B, Bitterlich N, Stehle P, Metzner C: Change in the fatty acid pattern of erythrocyte membrane phospholipids after oral supplementation of specific fatty acids in patients with gastrointestinal diseases. European Journal of Clinical Nutrition 2010 Apr;64(4):410-8. doi: 10.1038/ejcn.2009.151

Boesch-Saadatmandi C, Toedter Posspisil R, Graeser A, Canali R, Virgili F, Boomgaarden I, Doering F, Wolffram S, Egert S, Müller MJ, Rimbach G: Effect of quercetin on paraoxonase 2 levels in RAW264.7 macrophages and in human monocytes - role of quercetin metabolism. International Journal of Molecular Sciences 2009, 10(9): 4168-77.

Egert S, Bosy-Westphal A, Seiberl J, Kürbitz C, Settler U, Plachta-Danielzik S, Wagner AE, Frank J, Schrezenmeir J, Wolffram S, Rimbach G, Müller MJ: Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study. British Journal of Nutrition 2009, 102(7): 1065-74.

Egert S, Kannenberg F, Somoza V, Erbersdobler HF, Wahrburg U: Dietary alpha-linolenic acid, eicosapentaenoic acid or docosahexaenoic acid have differential effects on LDL fatty acid composition, but similar effects on fasting serum lipid profiles in normolipidaemic humans. Journal of Nutrition 2009, 139(5): 861-868.

Egert S, Fobker M, Andersen G, Somoza V, Erbersdobler HF, Wahrburg U: Effects of dietary alpha-linolenic acid, eicosapentaenoic acid or docosahexaenoic acid on parameters of glucose metabolism in healthy volunteers. Annals of Nutrition & Metabolism 2008, 53(3-4): 182-187.

Egert S, Wolffram S, Bosy-Westphal A, Boesch-Saadatmandi C, Wagner AE, Frank J, Rimbach G, Müller MJ: Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans. Journal of Nutrition 2008, 138(9): 1615-1621.

Egert S, Rassoul F, Boesch-Saadatmandi C, Richter V, Rimbach G, Erbersdobler HF, Somoza V, Wahrburg U: Effects of controlled diets enriched with alpha-linolenic acid, eicosapentaenoic acid or docosahexaenoc acid on soluble adhesion molecules and endothelin-1 concentrations in healthy volunteers. Current Topics in Nutraceutical Research 2007, 5(4): 189-196.

Egert S, Somoza V, Kannenberg F, Fobker M, Krome K, Erbersdobler HF, Wahrburg U: Influence of three rapeseed oil rich diets, fortified with alpha-linolenic acid, eicosapentaenoic acid or docosahexaenoic acid on the composition and oxidizability of low density lipoproteins: results of a controlled study in healthy volunteers. European Journal of Clinical Nutrition 2007, 61(3): 614-625.

Jochum F, Colling S, Meinardus P, Alteheld B, Stehle P, Fusch C: Total glutamine content in human milk is not influenced by gestational age. Acta Paediatrica 2006 Aug;95(8):985-90. doi: 10.1080/08035250600729100.

Alteheld B, Evans ME, Gu LH, Ganapathy V, Leibach FH, Jones DP, Ziegler TR: Alanylglutamine dipeptide and growth hormone maintain PepT1-mediated transport in oxidatively stressed Caco-2 cells. Journal of Nutrition 2005 Jan;135(1):19-26. doi: 10.1093/jn/135.1.19.

Jacobs B, Angelis-Schierbaum G, Egert S, Assmann G, Kratz M: Individual serum triglyceride responses to high-fat and low-fat diets differ in men with modest and severe hypertriglyceridemia. Journal of Nutrition 2004, 134(6): 1400-1405.

 

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